Discover Letybo® at Our La Jolla Med Spa: Premium Results, Proven Performance
Why Letybo® (letibotulinumtoxinA) Is a Top Choice for Wrinkle Relaxation
If you’re seeking a neurotoxin that delivers natural-looking results, high efficacy, and a strong safety profile, Letybo® may be the right choice for you. This FDA-approved botulinum toxin type A treatment is designed to smooth moderate to severe glabellar lines (the “11s” between the brows), and it’s already well known across Asia and Europe for its performance and purity.
Clinically Proven Results
Letybo’s FDA approval was based on three large-scale, double-blind clinical trials (BLESS I–III), which collectively studied over 1,200 adults with moderate to severe frown lines. These studies found that:
Between 46 to 65 percent of patients saw at least a two-grade improvement in their frown line severity after just four weeks.
In the BLESS III study, 65 percent of participants reported that their lines had improved to "none" or "mild" by week four (U.S. Food and Drug Administration, 2024).
These outcomes are consistent with the performance of established neurotoxins already in clinical use, making Letybo a competitive and trustworthy option.
Fast Onset and Reliable Duration
Clinical data and real-world experiences suggest that Letybo has a rapid onset of action, with some patients noticing improvements as early as two to three days after injection. Full results are typically visible within seven days. The effects of Letybo generally last about three to four months, similar to other botulinum toxins (PopSugar, 2025).
Advanced Purity and Safety Profile
Letybo is manufactured using an advanced double-chromatography purification process. This results in a high-purity neurotoxin with minimal inactive proteins, which may reduce the potential for immunogenic reactions—especially important for patients receiving repeated treatments.
In the FDA trials, side effects were mild and typical of botulinum toxin treatments, including temporary bruising, headaches, or slight muscle weakness. No serious adverse effects were reported at a higher rate than placebo (FDA, 2024).
A More Affordable Option
In addition to its clinical effectiveness, Letybo offers a price advantage compared to many neurotoxins on the market. On average, treatment with Letybo may cost 30 to 40 percent less per unit than Botox®, depending on the provider and market. This makes it a compelling choice for clients seeking high-quality results with better cost efficiency (New York Post, 2025).
Why Choose Letybo at Our La Jolla Med Spa?
Clinically proven to smooth glabellar lines.
Fast results, often within 2–3 days.
Similar duration to other top neurotoxins—around 3 to 4 months.
Highly purified to reduce potential for immune resistance.
Affordable without sacrificing quality.
Administered by licensed medical professionals with an emphasis on natural results.
At our La Jolla med spa, we personalize every injectable treatment to enhance your natural features while maintaining facial expression and balance. Whether you’re preparing for a special event or want to refresh your everyday appearance, we’re here to provide results you can trust.
Frequently Asked Questions About Letybo
How many units will I need?
For glabellar lines, the FDA-approved dose is 20 units, distributed across five injection sites between the eyebrows. Off-label dosing for other areas such as the forehead, crow’s feet, jawline, or masseters will be determined based on your anatomy and aesthetic goals.
Is Letybo safe?
Yes. It has undergone rigorous clinical trials and is approved by the FDA for cosmetic use. Side effects are generally mild and temporary.
How quickly will I see results?
Some patients begin to see changes in 2 to 3 days, with full results typically visible within 7 days.
How long do the effects last?
Most patients experience results that last around 3 to 4 months, though this can vary depending on metabolism and treatment area.
Can Letybo be used in areas other than the glabella?
Yes. Although it is FDA-approved for frown lines, experienced injectors frequently use it off-label for forehead lines, crow’s feet, lip flips, masseter slimming, and even underarm sweating (hyperhidrosis).
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Book Your Consultation Today
At Wonder Aesthetics in La Jolla, we believe in using science-backed solutions to help you look and feel your best. Letybo offers a balance of performance, purity, and affordability that makes it a smart choice for wrinkle reduction. Book your consultation today to learn more and find out if Letybo is right for you.
References (APA Style)
U.S. Food and Drug Administration. (2024). Drug Trials Snapshots: LETYBO. https://www.fda.gov
Hugel America, Inc. (2024, March 4). FDA approval of Letybo® for glabellar lines [Press release].
Allure. (2025, March 7). Everything you need to know about Letybo. https://www.allure.com
PopSugar. (2025, June 3). There’s a new Botox alternative on the block. https://www.popsugar.com
New York Post. (2025, March 12). Botox’s biggest rival lands in the US. https://nypost.com
MedEsthetics Magazine. (2025). K-beauty Letybo brings high-purity botulinum toxin A to US market. https://www.medestheticsmag.com
